Irvine is a town and former royal burgh on the coast of the Firth of Clyde in North Ayrshire, Scotland. The 2011 Census recorded the town's pop…Irvine is a town and former royal burgh on the coast of the Firth of Clyde in North Ayrshire, Scotland. The 2011 Census recorded the town's population at 33,698 inhabitants, making it the largest settlement in North Ayrshire, and 22nd largest settlement in Scotland.